Cholesterol & Lipoproteins
Cholesterol is an essential component of cell membranes and hormones. In the blood, it is transported as HDL and LDL; the balance between these is a key cardiovascular risk marker, strongly influenced by AAS.
Auch bekannt als: HDL, LDL, Lipoproteine, Blutfette, Cholesterol
Cholesterol. Not just harmful
Cholesterol is essential: a building block of cell membranes and Starting material for all steroid hormones (testosterone, cortisol, estrogen) → Steroid synthesis from cholesterol. The body produces most of it itself.
Transport: lipoproteins
- Cholesterol is fat-soluble and needs transport particles in the blood
- LDL (“bad”): brings cholesterol to the tissues; excess is deposited in vessel walls (arteriosclerosis)
- HDL (“good”): transports cholesterol back to the liver, protectively
- Ratio and particle number are more meaningful than the overall value
Cardiovascular risk
- High LDL + low HDL → arteriosclerosis → heart attack/stroke → Blood circulation & blood vessels
- Part of standard monitoring → Laboratory monitoring
AAS & blood lipids
- Oral AAS in particular severely worsen the lipid profile: HDL↓, LDL↑ → increased heart risk → Cardiovascular risks associated with AAS
- Countermeasures: cardio, omega-3, fiber, healthy fats → Omega-3, Citrus Bergamot
Nutrition
Dietary cholesterol influences blood values less than long thought; saturated fats and, above all, genetics play a role → Lipids & fatty acids.
Sources
- Grundy SM et al. AHA/ACC guideline on the management of blood cholesterol. Circulation. 2019. PubMed
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