Energy metabolism

Three energy systems provide ATP for muscle contraction. Phosphagen system (explosive), glycolysis (anaerobic), oxidative phosphorylation (aerobic), time frame and intensity determine which dominates.

Auch bekannt als: ATP-Synthese, Energiesysteme, aerober Stoffwechsel, anaerober Stoffwechsel

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ATP, the only energy currency

Muscles can only use adenosine triphosphate (ATP) directly for contraction, not fat, not glucose directly. All three energy systems serve ATP resynthesis. The body only has ~80-100g of ATP stored, enough for ~2-3 seconds of maximal work.

1. Phosphagen system (ATP-PCr)

  • Energy: Phosphocreatine → ADP + Pi → ATP
  • Capacity: 5-15 seconds maximum intensity
  • Advantage: immediately available, no oxygen required
  • Relevance: sprints, maximum weights, explosive movements
  • Creatine supplementation increases PCr stores by ~20%

2. Glycolysis (anaerobic-lactacid)

  • Glucose → pyruvate → lactate + 2 ATP (fast) or pyruvate → acetyl-CoA (aerobic)
  • Capacity: 15 seconds, 2 minutes
  • Lactate is not a “waste product”, it is an energy source (Cori cycle)
  • Relevance: 200-800m run, intense sets of 8-15 reps

3. Oxidative phosphorylation (aerobic)

  • Glucose, fatty acids, amino acids → CO₂ + H₂O + 30-32 ATP
  • Capacity: minutes to hours
  • Main energy system at continuous load < 70% VO₂max
  • Relevance: endurance training, basal metabolic rate, regeneration

Sources

  1. Hargreaves M, Spriet LL. Skeletal muscle energy metabolism during exercise. Nat Metab. 2020. PubMed

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